Appointments:
Orthopedic Surgeon
Colorado Limb Consultants
1601 E. 19th Avenue, Suite 3300
Denver, Colorado 80218
(303) 837-0072 / FAX (303) 837-0075

Medical Director
The Denver Clinic for Extremities at Risk
(formerly The Institute for Limb Preservation)
Presbyterian/St. Luke’s Medical Center
1601 E. 19^th Avenue, Suite 3250
Denver, Colorado 80218
(303) 832-5462

Medical Director
AlloSource
6278 So. Troy Circle
Centennial, Colorado 80111
(720) 873-0213

Chairman & Founder
The Limb Preservation Foundation
1600 Broadway Street, Suite 2400
Denver, CO 80202
(303) 542-1944

Affiliate Faculty Member
Colorado State University
Department of Clinical Sciences
Fort Collins, Colorado 80523

Education:
M.S. Physiology; course work completed 1974
Wayne State University School of Medicine, 1978
Research for Master's thesis conducted 1974-78 during medical school, entitled Von Willebrand Platelet Vessel Wall Interactions.

M.D. Wayne State University School of Medicine, 1978

Internship University of Colorado Health Sciences Center
Department of Surgery, 1978-79

Residency University of Colorado Health Sciences Center
Orthopedics, 1979-83

Fellowship Orthopaedic Oncology (Bone and Soft Tissue Tumors) Mayo Clinic, Rochester, Minnesota, 1983-84.

Honors and Awards:
Denver Business Journal’s Lifetime Champion in Healthcare, 2007
Top Doctors in Denver, Orthopedic Surgery, 2007
America's Top Doctors, Orthopedic Oncology, 2006-2008
Best Doctors in America – Orthopaedic Oncology, 1994-2008
The Ross M. Wilkins Limb Preservation University Chair at the CSU Animal Cancer Center to insure the continuation of extremity research in the State of Colorado, 2006
George W. Hyatt Memorial Award, 1999 [outstanding individual who demonstrates superior research, teaching & service abilities in the field of tissue banking and transplantation medicine]

Positions of Distinction:
American Academy of Orthopaedic Surgeons, Biological Implants Committee, 2007-2010
Physicians Council, Vice Chair, 2008-2009
American Association of Tissue Banks, Physicians Council Representative, 2006 – present
American Association of Tissue Banks, Vice Chair, 2008 – 2010
Donor Alliance, Medical Advisory Board, 2001- present
AlloSource, Senior Medical Director, 1995 - present
Limb Preservation Foundation, Founder & Chairman, 1986 – present
Musculoskeletal Tumor Society, President, 1998-1999
Colorado State University, Department of Clinical Sciences, Affiliate Faculty Member, 1994 - present
University of Colorado Health Sciences Center, Assistant Clinical Professor, Department of Orthopedics, 1984 – 1995
Orthopedic Research & Education Foundation, Research Grant Peer Review Committee, 1993
American Academy of Orthopaedic Surgeons, Committee on Musculoskeletal Tumors & Disease, 1992 – 1995
Presbyterian/St. Luke’s Medical Center, Chief of Department of Orthopedics, 1988, 1992, 1993, 1994
Presbyterian Denver Hospital, Chief of Department of Orthopedics, 1986 – 1989

Professional organizations
American Association of Tissue Banks
American Medical Association
Colorado State Medical Society
The CyberKnife Society
American Board of Orthopaedic Surgeons
International Society for Limb Salvage
International Society of Fracture Repair
Mayo Clinic Alumni Association
Musculoskeletal Tumor Society
Western Orthopedic Association

Research
Computerized Tomogram to Assess Bone Healing Following Grafting with PRODENSE Bone Graft, Wright Medical Technology, Participating Physician, 2007-present.

Repiphysis^TM Prosthesis, FDA Compassionate Release Status (for hip and shoulder applications), Co-Investigator, 2003 – present.

The Genomic Assessment of Clinical Variability in OGS, Mayo Clinic, Rochester MN, Principal Investigator, 2003 – present.

Use of Autoclaved Autograft for Reconstruction Following Tumor Resection, Principal Investigator, 2003-2008.

Use of the Expandable Fixion® Intramedullary Nailing Systems for the Treatment of Skeletal Metastasis in the Lower and/or Upper Limbs, Disc Orthopaedic Technologies, Inc., Co-Investigator, 2004-2005.

Allograft Retrieval Study, Colorado State University Biomedical Engineering Program, Principal Investigator, 2001-05.

Allomatrix^TM Injectable Putty Clinical Study, Wright Medical Technology, Participating Physician, 1999-2001.

Osteoset T® Biodegradable Beads, Small Group Access Treatment Arm, Wright Medical Technology, Co-Investigator 1999-2000.

Osteoset® Pellets, Product Evaluation Study, Wright Medical Technology, 1998 – 1999.

Publications
1. Fisher MM; Halpern GJ; Wilkins RM: Lymph cysts or lymphocoele: A case report. Angiology 36:832-8, 1985.
2. Sim FH; Bowman WE Jr; Wilkins RM; Chao ES: Limb salvage in primary malignant bone tumors. Orthopedics 8:574-81, 1985.
3. Wilkins RM; Winter WG: Complications of treatment of fractures and dislocation of the hip. In Epps CH (ed): Complications of Orthopedic Surgery, 2nd ed., Vol. I. Lippincott, Philadelphia PA, 1986.
4. Wilkins RM; Pritchard DJ; Burgert EO Jr; Unni KK: Ewing's sarcoma of bone; experience with 140 patients. Cancer 58:2551-5, 1986.
5. Wilkins RM; Sim FH: Evaluation of bone and soft tissue tumors. In D'Ambrosia R (ed): Musculoskeletal Disorders: Regional Examination and Differential Diagnosis, 2nd ed. Lippincott, Philadelphia PA, 1986.
6. Wilkins RM; Sim FH: Lesions of the femur. In Sim FH (ed): Diagnosis and Management of Metastatic Bone Disease. Raven Press, NY, 1988.
7. Wilkins RM; Fink K; Odom LF; Jamroz B; Stevens S; Peck S: Intra-arterial cisplatinum and intravenous Adriamycin in the treatment of osteosarcoma and malignant fibrous histiocytoma of bone. Early surgical and clinical results. Chir Organi Mov 75(1 suppl):50-3, 1990.
8. Withrow SJ; Powers BE; Straw RC; Wilkins RM: Comparative aspects of osteosarcoma: Dog versus man. Clin Orthop 270:159-168, 1991.
9. Wilkins RM; Sim FH; Springfield DS: Metastatic disease of the femur. Orthopedics 15:621-630, 1992.
10. Pals SD; Wilkins RM: Giant cell tumor of bone treated by curettage, cementation and bone grafting. Orthopedics 15:703-708, 1992.
11. Wilkins RM; Stringer EA: Demineralized cortical bone powder: Use in grafting space occupying lesions of bone. Int Orthop 2:71-78, 1994.
12. Gitelis S; Wilkins RM: Benign bone tumors. J Bone Joint Surg 77A:1756-82, 1995.
13. Wilkins RM: Complications of allograft reconstruction for skeletal defects following oncological surgery. In Simon MA; Springfield D (eds): Surgery for Bone and Soft-Tissue Tumors [Chapter 37]. Lippincott-Raven, Philadelphia, 1997, pp. 487-96.
14. Noyes FR, Barber-Westin SD, Butler DL, Wilkins RM: The role of allografts in repair and reconstruction of knee joint ligaments and menisci. Instr Course Lect 47:379-95, 1998.
15. Wilkins RM, Kelly CM, Giusti DE: Bioassayed demineralized bone matrix and calcium sulfate: Use in bone grafting procedures. Ann Chirurg Gynaecol 88:180-5, 1999.
16. Wilkins RM: Clinical effectiveness of demineralized bone matrix assayed in human cell culture. Adv Tissue Banking, 3(2.4):113-24, 1999.
17. Wilkins RM: Unicameral bone cysts. J A A O S 8:217-24, 2000.
18. Kelly CM, Wilkins RM, Gitelis S et al: The use of a surgical grade calcium sulfate as a bone graft substitute: Results of a multi-center trial. Clin Orthop 382:42-50, 2001.
19. Wilkins RM, Soubeiran A: The Phenix expandable prosthesis: early American experience. Clin Orthop 382:51-8, 2001.
20. Ferreira SD, Dernell WS, Powers, BE, Schochet RA, Kuntz CA, Withrow SJ, Wilkins RM: Effect of gas-plasma sterilization on the osteoinductive capacity of demineralized bone matrix. Clin Orthop 388:233-9, 2001.
21. Wilkins RM: Treatment of benign bone tumors. In Menendez LR (ed): Orthopaedic Knowledge Update, Musculoskeletal Tumors, pp.77-85. American Academy of Orthopaedic Surgeons, Rosemont IL, 2002.
22. Wilkins RM, Kelly CM: Revision of the failed femoral replacement to allograft prosthetic composite. Clin Orthop 397:114-8, 2002.
23. Wilkins RM, Hinshaw, I: Osteogenic sarcoma (Chapter 78). In Wood ME; Philips GK (eds): Hematology/Oncology Secrets (3^rd ed.). Hanley & Belfus, Inc., Philadelphia, 2003, pp. 372-4.
24. Wilkins RM, Hinshaw I: Soft tissue sarcomas (Chapter 79). In Wood ME; Philips GK (eds): Hematology/Oncology Secrets (3^rd ed.). Hanley & Belfus, Inc., Philadelphia, 2003, pp.374-7.
25. Wilkins RM, Chimenti BT, Rifkin RM: Percutaneous treatment of long bone nonunions: The use of autologous bone marrow and allograft bone matrix. Orthopedics 26(suppl):s549-54, 2003.
26. Wilkins RM, Kelly CM: The effect of AlloMatrix™ injectable putty on the outcome of long bone applications. Orthopedics 26(suppl):s567-70, 2003.
27. Wilkins RM, Cullen JW, Odom L, Jamroz BA, Cullen PM, Fink K, Peck SD, Stevens SL, Kelly CM, Camozzi AB: Superior survival in treatment of primary non-metastatic pediatric osteosarcoma of the extremity. Ann Surg Oncol 10:498-507, 2003.
28. Wilkins RM, Miller CM: Reoperation after limb preservation surgery for sarcomas of the knee in children. Clin Orthop 412:153-61, 2003.
29. Kelly CM, Wilkins RM, Eckardt JJ, Ward WG: Treatment of metastatic disease of the tibia. Clin Orthop 415(suppl):s219-29, 2003.
30. Neel MD, Wilkins RM, Rao BN, Kelly CM: Early multicenter experience with a noninvasive expandable prosthesis. Clin Orthop 415:72-81, 2003.
31. Gitelis S, Neel MD, Wilkins RM, Rao BN, Kelly CM, Yao TK: The use of a closed expandable prosthesis for pediatric sarcomas. Chir Organi Mov 88:327-33, 2003.
32. Kelly CM, Wilkins RM: Treatment of benign lesions of bone with an injectable calcium sulfate-based bone graft substitute. Orthopedics 27[suppl]:s131-5, 2004.
33. Wilkins RM: Clinical effectiveness of demineralized bone matrix assayed in human cell culture. In Phillips GO (ed.): Bone Biology and Healing. Allografts in Bone Healing: Biology and Clinical Applications, Vol. 1. World Scientific Publ, River Edge NJ, 2004.
34. Wilkins RM, Brown WC: Upper extremity salvage and reconstruction for trauma and tumors. In Meier RH, Atkins DJ (eds.): Functional Restoration of Adults and Children with Upper Extremity Amputation. Demos Medical Publ., New York NY, 2004, pp. 23-33.
35. Wilkins RM, Kelly CM, Hahn DB: Use of a calcium sulfate-based bone substitute [abstract]. Symposium of the 15^th Interdisciplinary Research Conference on Biomaterials. J Med Biomech 20[suppl]:10-11, 2005.
36. Cullen JW, BA Jamroz MD, SL Stevens MD, et al: The value of serial arteriography in osteosarcoma: delivery of chemotherapy, determination of therapy duration and prediction of necrosis. J Vasc Interv Radiol 16:1107-19, 2005.
37. Wilkins RM, Cullen JW, Camozzi AB, et al: Improved survival in primary nonmetastatic pediatric osteosarcoma of the extremity. Clin Orthop 438:128-36, 2005.
38. Wilkins RM, Camozzi AB, Gitelis SB: Reconstruction options for pediatric bone tumors about the knee. [In Gitelis S (ed), Special Focus Section], J Knee Surg 18:305-9, 2005.
39. Wilkins RM, Kelly CM: Unicameral bone cysts. In Sahni V, Frostick S (eds.): The Liverpool Book of Orthopaedics. The University of Liverpool, Liverpool, UK (in press).
40. Hugate RR, Wilkins RM, Kelly CM, Madsen W, Hinshaw I, Camozzi AB. Intraarterial Chemotherapy for Extremity Osteosarcoma and MFH in Adults. Clin Orthop Relat Res. 2008;466:1292-1301.

Presentations
1. The Use of Allograft Bone in General Orthopaedics. Symposium on Current Trends in Bone Grafting, Denver CO, May, 1986.
2. Intra-arterial and Intravenous Preoperative Chemotherapy for Treatment of Osteosarcoma. Fitzsimons Army Hospital Annual Symposium on Children's Orthopedics, Aurora CO, March, 1989.
3. Demineralized Bone Powder: Use in Space Occupying Lesions of Bone. International Society of Fracture Repair. Mayo Clinic, Rochester MN, September, 1990.
4. Limb Salvage for Malignant and Extremity Tumors. Sixty-fourth Annual Clinical Assembly of Osteopathic Specialists, American Osteopathic Academy of Orthopedics. Orlando FL, September 28-October 1, 1991.
5. Limb Preservation for Malignant Extremity Tumors. Western Orthopaedic Association, Rocky Mountain Chapter Summer Meeting (Session VIII Moderator). Aspen, CO, August 1, 1992.
6. Bone Banking as It Relates to Allografting. Reconstructive Surgery of the Hip and Knee. Durango CO, January 26, 1993.
7. The Use of Cemented Allografts in Limb Salvage Procedures. Annual Summer Meeting of the Rocky Mountain Chapter of the Western Orthopaedic Association, Aspen CO, July 29-31, 1994.
8. Treatment of Benign Bone Tumors: Removal and Reconstruction. Instructional Course, Annual Meeting of the American Academy of Orthopaedic Surgeons, Orlando FL, February 16-21, 1995.
9. Proximal Humeral Allograft Replacement for IIB Sarcomas of the Shoulder. Sixth Asia Pacific Association of Surgical Tissue Banks Scientific Meeting, Queensland, Australia, October 2-5, 1996.
10. Treatment of Stiff Nonunions with Bone Matrix/Bone Marrow Percutaneous Injections. Sixth International Conference on Tissue Banking, Edinburgh, Scotland, October 28-31, 1997.
11. Fixation of Femoral and Tibial Shaft Metastases: Intramedullary Rodding. The 65th Annual Meeting of the American Academy of Orthopaedic Surgeons, Musculoskeletal Tumor Society Specialty Day, New Orleans LA, March 19-23, 1998.
12. Functional Results of Reoperation in Pediatric Limb Salvage patients with Malignancies About the Knee. The 10th International Symposium on Limb Salvage (ISOLS), Cairns, Queensland, Australia, April 11-14, 1999.
13. ALLOMATRIX^TM Injectable Putty: An Osteoinductive Bone Grafting Material. Wright Medical Technology European Meeting, Athens, Greece, May 4-5, 2000.
14. The Use of Demineralized Bone Matrix (DBM) and Calcium Sulfate (Osteoset®) as a Bone Graft Substitute for Benign Lesions of Bone. Annual Meeting of the American Academy of Orthopaedic Surgeons, San Francisco CA, March 4, 2001.
15. Revision of the Revision TKR. Wright Medical Technology, Vail CO, August 24, 2001.
16. Revision of the Revision TKR Total Joint Arthroplasty Current Issues, Concepts & Considerations, Vail CO, August 24-25, 2001.
17. Modern Treatment of Orthopaedic Infections. Indiana Orthopaedic Society 46^th Annual Conference, Indianapolis IN, April 11-13, 2002.
18. The Accuracy of Preoperative Serial Arteriograms in Predicting Tumor Necrosis in Pediatric Osteosarcoma: Impact on Surgical Decision-Making. MSTS Annual Meeting, Toronto, Ontario, Canada, April 25-27, 2002.
19. Advances in Bone Grafting. Grand Rounds, Wake Forest University Baptist, Winston Salem NC, May 22, 2002.
20. Allografts and Bone Replacement Materials: How Do I Choose? Bone & Soft Tissue Tumor Conference, Carolinas Medical Center, Charlotte NC, May 23, 2002.
21. The Use of CaSO₄ in Combination with DBM. Wright Medical Technology and the Joint Replacement Institute at Orthopaedic Hospital, Vienna, Austria, June 21-22, 2002.
22. Early Experience with a Novel Expandable Prosthesis. Wright Medical Technology and the Joint Replacement Institute at Orthopaedic Hospital, Vienna, Austria, June 21-22, 2002.
23. Management of the Infected Prosthesis. Puerto Rican Society of Orthopedics & Traumatology, Dorado, Puerto Rico, August 30-September 2, 2002.
24. Orthopaedic Infections: A Rationale for Treatment. Montana Orthopaedic Society Annual Meeting, Billings MT, January 17-19, 2003.
25. Expandable Implants: Factors Influencing Selection. Symposium on Limb Salvage in the Growing Child: Principles & Practice. MSTS Specialty Day, AAOS Annual Meeting, New Orleans LA, Feb. 8, 2003.
26. Decalcified Bone Matrix. First British Symposium on Growth Factors and Bone Morphogenic Proteins as Relevant to Orthopaedic Surgery, London, June 11, 2003.
27. Bone Graft Substitutes. American Orthopaedic Foot & Ankle Society Specialty Day, San Francisco, March 13, 2004.
28. Human Allografts: Complications & Solutions. Symposium on Organ & Tissue Donation, Mid-America Transplant Services, St. Louis, April 2, 2004.
29. The Science & Clinical Applications of Calcium Sulfate and Demineralized Bone Matrix. Changzheng Hospital, Hangzhou, China, April 28, 2004.
30. Fresh Joint Transplantation: Indications & Early Results. Combined Meeting of the Rocky Mountain & Western Slope Chapters of the Western Orthopaedic Association, Annual Summer Meeting, Beaver Creek CO, August 6-7. 2004.
31. Superior Survival in Treatment of Primary Non-Metastatic Pediatric Osteosarcoma of the Extremity. Colorado Cancer Coalition, Denver CO, August 9, 2004.
32. Bioactive Materials. 17^th Annual Symposium of the International Society for Technology in Arthroplasty. Rome, Italy, September 23-25, 2004.
33. Human-Derived Bone Growth Factors: Innovative System for Delivery and Use. 17^th Annual Symposium of the International Society for Technology in Arthroplasty. Rome, Italy, September 23-25, 2004.
34. Pediatric Osteosarcoma: Improved Survival. Australian Sarcoma Society, NOOSA, Queensland, Australia, October 24, 2004
35. The Non-Invasive Expandable Prosthesis. The 11^th Meeting of the Combined Orthopaedic Associations. Sydney, Australia, October 26-29, 2004.
36. Femoral Endoprosthetic Replacement. The 11^th Meeting of the Combined Orthopaedic Associations. Sydney, Australia, October 26-29, 2004.
37. Biodegradable Antibiotic Beads. The 11^th Meeting of the Combined Orthopaedic Associations. Sydney, Australia, October 26-29, 2004.
38. Use of a Calcium Sulfate-Based Bone Substitute. 15^th Interdisciplinary Research Conference on Biomaterials, Shanghai, China, March 18-20, 2005.
39. Surgical Principles of Bone Healing. Pacific Rim Orthopaedic Update, Kapalua HI, August 27-28, 2005.
40. Treatment of Infected Arthroplasties: An Update. 37^th Congresso Brasileiro de Ortopedia ou Tramatologia, Rio de Janeiro, Brazil, Oct. 29 – Nov. 1, 2005.
41. Bone Graft Substitutes: How Do I Choose? 37^th Congresso Brasileiro de Ortopedia ou Tramatologia, Rio de Janeiro, Brazil, Oct. 29 – Nov 1, 2005.
42. Update on Osteosarcoma. Keynote Speaker, Symposium on Canine Osteosarcoma, Veterinary Cancer Society, Sedona AZ, March 5-8, 2006.
43. Starting a Tissue Bank. (Invitation from the President of Sicily.) Palermo, Italy, April 8-13, 2006.
44. Large Bone Defects. Australian Orthopaedic Association, Gold Coast, Queensland, Australia, July 10-12, 2006.
45. Progress in Bone Healing. Fourth Annual Celje Days Symposium, Celje, Slovenia, March 23-24, 2007.
46. Allograft Transplantation to Lengthen Trans-Humeral Amputation Limbs. The 12th World Conference of the International Society for Prosthetics and Orthotics, Vancouver, Canada, July 29 - August 3, 2007.
47. Distal Femoral Replacement for Nontumors. American Orthopaedic Association, North American Travelling Fellowship Meeting, Porter Hospital, Denver CO, October 25, 2007.
48. Repiphyisis. Invited lecture, Chinese Orthopaedic Association, November 11-17, 2007.
49. Limb Preservation in the Growing Child. Invited lecture, Hong Kong Orthopaedic Association, November 11-17, 2007.
50. GRAFTJACKET^® Matrix: Additional Applications in Orthopaedics. Reinforcement of Chronic Quadriceps Ruptures Using GRAFTJACKET^® Matrix. GRAFTJACKET^® Regenerative Tissue Matrix Symposium on Orthopaedic Soft-Tissue Regeneration, Wright Medical, Dallas TX, November 7-8, 2008.